DENVER -- Even when the San Francisco Giants pick up a rare win at Coors Field, they still lose. In this case, two pitchers -- starter Matt Cain and reliever Santiago Casilla, who both strained their right hamstrings and will undergo MRIs to determine the severity. Hunter Pence hit one of San Franciscos three solo homers and reliever Yusmeiro Petit threw three sharp innings after Cain left as the Giants beat the Colorado Rockies 5-1 on Wednesday night. "The win was great," Pence said, "but its a huge blow to lose Cain and Casilla." Pablo Sandoval and Brandon Crawford also connected for the NL West-leading Giants, who won at this hitter friendly venue for just the fifth time in 15 games dating back to last season. Cain had good command and was cruising along, not allowing a hit through three innings. Then, on his last pitch of the third, he felt a twinge in his hamstring. Casilla was hurt in the ninth inning when he tried to beat out an infield hit, falling over the bag and rolling several times on the field. He was helped to the dugout by the trainers and was replaced on the mound by Jeremy Affeldt, who finished the game. To think, just moments before in the dugout, Giants manager Bruce Bochy told Casilla to not even bother swinging -- just take it easy at the plate. "I was shocked he was running like that," Bochy said. "Guess he thought he had a hit. I dont know what got into him. Never seen him run like that." Petit (3-1) pitched effectively in Cains place as he and four other relievers limited the best offensive team in the majors to just five hits. Jhoulys Chacin (0-3) worked 5 2-3 innings and allowed three runs, including a homer to Pence in the fourth and another to Sandoval two innings later. "Two bad pitches, two homers, two runs," Chacin said. "I pitched good. We lost and thats all I care about." Crawford added a solo shot off Matt Belisle in the seventh as the Giants took the middle contest to even the three-game series. The Rockies have yet to lose a series at home this year. Trailing 5-0 in the eighth, the Rockies loaded the bases with no outs. Michael Cuddyer sent a grounder up the middle that Crawford tracked down and scooped over to second base with his glove to start a double play. Troy Tulowitzki then flew out limit the damage to only a run. Cain was settling into a rhythm when Rockies second baseman D.J. LeMahieu sent a sharp comebacker at the right-hander in the third. While the ball glanced off Cains glove, the Giants came out to check on him. Cain said after the game that had nothing to do with his hamstring injury. Earlier this season, Cain missed 13 games after he cut his right index finger while making a ham-and-cheese sandwich in the Giants clubhouse. The cut didnt require stitches. Optimistic this injury will heal fast? "Well see how tomorrow it feels," Cain said. "Still got some adrenaline going. But its calming down." Carlos Gonzalez also was banged up as he left the game as part of a double-switch in the eighth because of inflammation in his left index finger. He said he had an X-ray during the game and its not broken. "One of those things I have to deal with and get treatment every day," the slugger said. Tulowitzkis torrid hitting at home this season (.521 with eight homers) caught the attention of Giants broadcaster and former major league pitcher Mike Krukow. "Youre always skeptical -- its just the way you are as a player," Krukow said before the game. "Hes hitting as if hes getting signs. Im not accusing anybody of anything." Still, Rockies manager Walt Weiss had some fun with the assertion his shortstop is somehow stealing signs. "We have a light bulb on the scoreboard we flash. Keep an eye on Dinger (the teams mascot), hes involved," Weiss said. "We switch out the balls. Got the umpires in on it. "I love it when other teams talk about that," Weiss said. "I think its great. I think it feeds the beast." NOTES: Bochy said Buster Posey (nerve irritation in lower back) is "doing a lot better" and the catcher could be in the lineup Thursday. ... RHP Tim Hudson (4-2) will take the mound in the series finale on Thursday. The Rockies will throw LHP Jorge De La Rosa (5-3). Byron Scott Lakers Jersey . PETERSBURG, Fla. Kareem Abdul-Jabbar Lakers Jersey . PETERSBURG, Fla. http://www.lakersteamofficial.com/ . Louis, MO (SportsNetwork. Nick Van Exel Lakers Jersey . Saltalamacchia drove in the go-ahead run in the ninth inning, Henderson Alvarez won for the first time in three starts and the Miami Marlins beat the Braves 3-2 on Thursday night. Kurt Rambis Jersey . -- LeBron James warned the Orlando Magic to stop double-teaming him and ignoring James Jones.NEW YORK -- The New York Jets have re-signed veteran linebacker Calvin Pace to a two-year deal, bringing back one of their sacks leaders from last season. Pace had a career-high 10 sacks for Rex Ryans defence-- second only to Muhammad Wilkersons 10 1/2 -- in his sixth season with the Jets. The 33-year-old outside linebacker was an unrestricted free agent. Pace, who played his first five NFL seasons with Arizzona, has 52 career sacks and has started every game the last three years.dddddddddddd He is likely to be slated to start opposite Quinton Coples again this season. The Jets cut Pace last off-season to save money under the salary cap before re-signing him last April. He rewarded them by having one of his best overall seasons, which included 53 tackles, two forced fumbles and three passes defenced. ' ' '